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Duration: 3 years

Program Coordinator: Prof. Riccardo Ghidoni

Training activities include:
Courses: courses include basic, specialized and science management topics
Seminars: advanced topics presented by well-known scientists
Research: the doctoral students work as active researchers


The program focus on the molecular basis of human diseases and therapeutics. It provides a multidisciplinary research environment integrating basic, applied, and clinical sciences, as well as a wide spectrum of experimental techniques.
The aim is to form a bridge between basic science and the clinic.

  • The thesis projects point at different aspects of genetic and metabolic diseases, inflammation, immunopathology and cancer.
  • Students learn how to carry out independent and original scientific work in a project-oriented training program.
  • They will meet regularly with a tutor for advice on the planning of their program and to discuss specific issues of their thesis project.
The final aim of the program is to train a scientist that will find a position at management levels, in academic research and clinical centres, in biotechnological industries and in other biomedical structures.

Main research topics

Genomics, Proteomics and related Technologies

Research topics include: molecular genetics, cytogenetics, cancer genetics, biochemical genetics, medical genetics, functional genomics, molecular and cell biology, genetic epidemiology, statistical genetics, and bioinformatics.

The research groups work on model organisms endowed with different complexity, from yeasts to humans, and apply a wide variety of methodologies and strategies in vitro, in silico, and in vivo.This broad range of research is a strong starting point to produce scientists trained in basic or applied translational research relevant to human health and disease.

Molecular Medicine in Immune Reaction and Inflammation

Research topics include: molecular and cellular immunology, immunopathology of autoimmune and allergic diseases, immunogenetics, molecular biology of immunodeficiencies, immunogenomics, immunobiology of cytokines and inflammation, antibacterial, antiviral and antiparasitic immune defenses

The work of the research groups covers a wide area from molecular to cellular immunology and from in vitro models to the whole organism. The response of the host are investigated at the genetic, molecular, and cellular levels. Special emphasis is on the mechanisms by which infectious agents (HIV, HHV8, HCV, malarial parasites) circumvent the normal immune response, on the response of the host to cancer and on the strategies to improve tumor surveillance. The multidisciplinary approach to immunology can lead to new understanding of disease, and to identification of novel therapeutic targets for controlling immunity and inflammation.

The program aims to prepare scientists for a career in biomedical research in academia, pharmaceutical companies, private research foundations, governmental research and regulatory agencies.

Molecular Oncology

Research topics: Gene transcription, signal transduction, growth factor biology, cancer genetics, DNA damage and repair, RNA and protein instability, genomic instabilities, cell differentiation, apoptosis, viral and cellular oncogenes, epigenetic control of tumor growth, angiogenesis.

The research groups work on in vitro and in vivo models, applying a multidisciplinary approach which encompasses techniques of molecular biology, biochemistry, genetics, genomics, proteomic, cell biology, and biostatistics. Students will interface with basic scientists and clinical oncologists/researchers to develop their research programs. Research topics covers a broad range including oncosuppressor genes and DNA repair genes, cooperation between oncogenes and neoplastic progression, transduction of the mitogenic signal, neoplastic transformation and regulation of cell differentiation, apoptosis.
The goal of this program is to train students in technologies that are relevant for advanced basic cancer research and to translate basic research into the setting of clinical oncology.

Academic board

Academic board

Director: Riccardo Ghidoni,
Full professor of Biochemistry
Academic board:

ABRIGNANI Sergio Settore Med/04 - Patologia Generale
BASILICO NICOLETTA Settore MED/04 - Patologia Generale
BATTAGLIA CRISTINA Settore BIO/10 - Biochimica
BLASI Francesco Bruno Arturo Settore MED/10-Malattie dell'Apparato Respiratorio
BIASIN MARA Settore BIO/13 - Biologia Applicata
BORGHI ELISA Settore MED/07 - Microbiologia e Microbiologia Clinica
BORSELLO TIZIANA Settore BIO/16 - Anatomia Umana
BOTTAI DANIELE Settore BIO/14 - Farmacologia
CACCIA SONIA Settore BIO/11 - Biologia Molecolare
CAPPELLINI MARIA DOMENICA Settore MED/09 - Medicina Interna
CANEVINI Maria Paola Settore MED/39- Neuropsichiatria Infantile
CARETTI ANNA Settore BI0/10- Biochimica
CHIARAMONTE RAFFAELLA Settore MED/04 - Patologia Generale
CLERICI MARIO Settore Med/04 - Patologia Generale
COMI GIACOMO PIETRO Settore MED/26 - Neurologia
CORTI STEFANIA PAOLA Settore MED/26 - Neurologia
COZZOLINO Mario Gennaro settore MED/14- Nefrologia
DEL BUE SERENA Settore MED/07 - Microbiologia e Microbiologia Clinica
DEL SOLE ANGELO Settore Med/36 - Diagnostica per Immagini e Radioterapia
DESIDERIO MARIA ALFONSINA Settore MED/04 - Patologia Generale
FAIONI ELENA MARIA Settore MED/09 - Medicina Interna
FALLENI MONICA Settore Med/08 - Anatomia Patologica
FENIZIA CLAUDIO Settore Med/04 - Patologia Generale
FERRANTE PASQUALE Settore MED/07 - Microbiologia e Microbiologia Clinica
FERRERO BOGETTO STEFANO Settore MED/08 - Anatomia Patologica
FENIZIA CLAUDIO Settore MED/04 -Patologia generale
FOLLI FRANCO Settore MED/13 - Endocrinologia
GAMBINI ORSOLA Settore MED/25 - Psichiatria
GELFI CECILIA Settore BIO/12 - Biochimica Clinica e Biol Mol Clinica
GHIDONI RICCARDO Settore BIO/10 - Biochimica
LUCIGNANI GIOVANNI Settore MED/36 - Diagnostica per Immagini e Radioterapia
LESMA Elena Anna Settore BIO/14 - Farmacologia
MAGGI Roberto Settore BIO/09-Fisiologia
MASSA VALENTINA Settore BIO/13 - Biologia Applicata
MIOZZO MONICA ROSA Settore MED/03 - Genetica Medica
NANO GIOVANNI Settore Med/22 - Chirurgia Vascolare
NEMNI RAFFAELLO Settore MED/26 - Neurologia
OTTOBRINI LUISA Settore MED/36 - Diagnostica per Immagini e Radioterapia
PEYVANDI Flora Settore Med/09 - Medicina Interna
PARAPINI SILVIA Settore MED/07 - Microbiologia e Microbiologia Clinica
ROSSETTI LUCA MARIO Settore MED/30 - Malattie Apparato Visivo
SACCHI NICOLETTA Settore BIO/11 - Biologia Molecolare
SAMAJA MICHELE Settore BIO/10 - Biochimica
SCARONE SILVIO Settore MED/25 - Psichiatria
SCARPINI ELIO ANGELO Settore MED/26 - Neurologia
SIGNORELLI PAOLA Settore BIO/10 - Biochimica
SIRCHIA SILVIA MARIA Settore MED/03 - Genetica Medica
SOLDATI LAURA Settore MED/49 - Scienze Tecniche Dietetiche Applicate
TABANO SILVIA Settore MED/03- Genetica Medica
TARAMELLI DONATELLA Settore MED/04 - Patologia Generale
TRABATTONI DARIA LUCIA Settore MED/04 - Patologia Generale
VAIRA VALENTINA Settore MED/08 - Anatomia Patologica
VIGNOLI AGLAIA Settore MED/39 - Neuropsichiatria Infantile

To contact single tutor, please go to main home page of Università degli studi di Milano:



Director: Prof. Riccardo Ghidoni
address: Dipartimento scienze della salute
Contact e-mail:

Webmaster Ariel
Dr.Cristina Battaglia
e-mail :

Call for application

PhD application for MMT

Doctoral programme activities fall within the framework of the "Life Sciences" and their biomedical application, providing students with an understanding of the biological and physiopathological basis for treating and preventing diseases. The main objective is to provide unifying cross-sector knowledge and technologies which, in the post-genomic era, can combine basic, formerly distinct medical disciplines (biochemistry, biology, molecular biology, physiology, pharmacology, general pathology, immunology, genetics, virology, anatomical pathology) with applied medical sciences and medical research. Long-standing collaborations with industries in the fields of diagnostics, pharmaceuticals, IT and design of scientific equipment will be strengthened. This proves the interest of biotechnological and biomedical companies, which consider the activities of this programme as a concrete opportunity to step into or strengthen their presence in a steadily developing sector. At the same time, these collaborations represent a job placement opportunity.
List of Research lines

For further information please contact : Prof. Riccardo Ghidoni

Number of positions : 10
8 with PhD unimi fellowship
2 without fellowship

All applicants are required to apply online within 4 September 2017 at 1 p.m

Info for application criteria, please see

Participation in the competitive examination for admission to the doctoral programmes is open to candidates who hold a 2nd cycle degree (master-level) awarded by an accredited foreign university and can demonstrate an English language proficiency at least at Level B2 of the Common European Framework of Reference for Languages (CEFR).
All applicants are required to apply online within 4 September 2017 at 1 p.m, according to the procedure